Design and Selection of IFI16-PAAD Mutants with Improved dsDNA Destabilization Properties

Desmond Lau^#, Kush Dalal^#, Benjamin Hon and Frederic Pio^*

Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr, Burnaby, British Columbia V5A 1S6, Canada

^#Contributed equally to this work

^*Corresponding Author: Frederic Pio, Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr, Burnaby, British Columbia V5A 1S6, Canada, Tel: 778-782-5660, Fax: 778-782-5583