Defining Conditions for Sustaining Epiblast Pluripotence Enables Direct Induction of Clinically-Suitable Human Myocardial Grafts from Biologics-Free Human Embryonic Stem Cells

James F. Parsons^1,2,3, David B. Smotrich^1,3,4, Rodolfo Gonzalez^1,3, Evan Y. Snyder^1,3, Dennis A. Moore^1,2,3 and Xuejun H. Parsons^1,2,3*

¹San Diego Regenerative Medicine Institute, San Diego, CA 92109, USA

²Xcelthera, San Diego, CA 92109, USA

³Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037, USA

⁴La Jolla IVF, La Jolla, CA 92037, USA

^*Corresponding Author: Xuejun H. Parsons, San Diego Regenerative Medicine Institute, San Diego, CA 92109, USA Email: