School of Cancer and Enabling Sciences, Paterson Institute for Cancer Research
University of Manchester, UK
During his undergraduate studies, Dr. Stephanos Pavlides, volunteered in Prof. Jan Breslow’s laboratory of Biochemical Genetics and Metabolism at The Rockefeller University, working on atherosclerosis. Later in 2004 during his graduate studies at Albert Einstein College of Medicine of Yeshiva University, he started his PhD research project in Prof. Michael Lisanti’s laboratory and then continued under his supervision at Thomas University Jefferson, in Philadelphia, until late 2010. During his PhD studies Dr. Pavlides investigated the biology of cancer stem cells and the role of Caveolin-1 protein in the tumor microenvironment. The fundamental insights gleaned from Dr. Pavlides’ scientific work on the microenvironment stromal cells linked tumorigenesis and metastasis based on the “reverse Warburg effect”. He is currently a Research Associate at Breakthrough Breast Cancer Research Unit and School of Cancer & Enabling Sciences, Paterson Institute for Cancer Research, at the University of Manchester. In parallel to his scientific career he has been actively involved in organizing various scientific seminars and other leadership roles.
His research direction is focused on developing a better understanding of breast cancer, leading to targeted therapies and personalized medicine.