Duke Human Vaccine Institute, Department of Medicine, Duke University Medical Center
Mattia BONSIGNORI is a Medical Instructor in the Department of Medicine at Duke University Medical Center, a Faculty member of the Duke Human Vaccine Institute and a member of the Duke Center for HIV/AIDS Research CFAR. He currently works at the Duke Human Vaccine Institute within the framework of the Center for HIV/AIDS Vaccine Immunology CHAVI. He was previously a postdoctoral associate in the Department of Immunology at St. Jude Children’s Research Hospital Memphis, Tennessee, USA. He earned a postgraduate degree in Clinical Microbiology and Virology 2005 and an M.D. 2001 from the University of Insubria Varese, Italy. He has authored several articles in various international scientific journals and currently serves as a peerreviewer for “HIV/AIDS – Research and Palliative Care”, “Clinical Epidemiology”, “International Journal of Interferon, Cytokine and Mediator Research”, “Infection and Drug Resistance”, “Virus adaptation and Treatment” and “Drug Design, Development and Therapy”.
HIV vaccine development Induction of broadly neutralizing antibodies to HIV Determination of correlates of protective immunity to HIV Biology of the generation and maintenance of protective immunological memory after infection or upon vaccination. Development of functional assays for the evaluation at a single-cell level of B-cell responses to vaccinations, infections and in vitro stimulation Epidemiology and characterization of bacterial resistance determinants (past).