Journal of Clinical & Experimental Pharmacology

Kogi State University, P.M.B 1008, Anyigba, Kogi State, Nigeria

Publications

• Research Article   
  Chemopreventive Effect of Methanol Extract of Anacardium Occidentale Nut Shell on Ultra-Violet Radiation Induced Skin Damage
  Author(s): Pepple NM, Ekoriko WU, Idih FM* and Chidozie VO
  
  Anacardium occidentale nut shell liquid which is mostly known as cashew nut shell liquid has been used for decades especially by natives of South America, Asia and Africa in the treatment of topical skin diseases, skin abrasion and cancerous ulcers amongst others. Some previous studies attempted to link pharmacological activities to the antibacterial, antioxidant and anti-proliferative properties of CNSL. Chronic exposure to sunlight can lead to skin damages including erythema, edema, hyperplasia, formation of sunburn cells, photoaging, suppression of the immune system and skin cancer. This study was aimed at evaluating the effect of methanol extract of Anacardium occidentale nut shell liquid on UV induced skin damage and cancer initiation. Gas chromatography and mass spectroscopic analysis was carried out on the extract. Skin damage was induced by exposing the hairless part of the ex.. View more»
  

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