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Gaurav Malhotra
Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, India
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Research Article
A Comparison of Resting Regional Cerebral Glucose Metabolism in Patients with Suicidal Attempts with and without Having a Major Depressive Disorder
Author(s): Shubhangi Parkar, Karishma Rupani*, Gaurav Malhotra, Natasha Kate and Trupti Upadhye Bannor
Background: Individuals with suicidal behaviors are increasingly recognized as having impairments in brain metabolism. However what differentiates those who attempt suicide while having diagnosable depression versus those who attempt suicide without depression, in terms of neurobiology is still largely unknown. Aims: Using the F-18 FDG brain positron emission tomography to: 1. To evaluate differences in resting Cerebral Glucose Metabolism (rCMglu) between depressed and non-depressed suicidal subjects. 2. To translate a suicide attempt, which is a behavioral construct (NSSI or otherwise) into neurobiological constructs. Methods: Patients with suicide attempt with diagnosable Depression and those with suicide attempt without diagnosable depression (NSSI) were included. Brain metabolism was assessed using .. View more»