Journal of Tumour Research & Reports

Journal of Tumour Research & Reports
Open Access

ISSN: 2684-1614


Ahu Pakdemirli

Dokuz Eylul University, Vocational School of Health Services, First and Emergency Aid Program, İzmir, Turkey

  • Research Article   
    The Effects of Quercetin on the Fluorosis Toxicity in Kidney of Mice
    Author(s): Ercan Karabulut*, Onder Otlu, Ahu Pakdemirli, Murat Yarım, Ayris Salt and Sena Cenesiz

    There are many uses of fluorine compounds which we are exposed to in daily life unaware, have toxic effects on tissues. Demonstrating anti-oxidative effect is one of the most important biological properties of phenolic substances. It has been identified in vitro studies of antioxidant flavonoids such as quercetin that it reduces the oxidation of lowdensity lipoproteins and protects cells from toxicity. In this study we aimed to determine the effect of quercetin on the fluorosis toxicity in kidney. In the study, 40 Swiss albino male mice were used. The kidney tissues and blood samples were taken from the mice in each group. Total Oxidant Status and Total Antioxidant Status were measured by the commercially available kits. Ceruloplasmin and MDA levels are measured by chlorometric methods. Kidney tissues stained with Hematoxylin-Eosin dye and investigated under the light microscope. Hist.. Read More»

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