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Abbas Muhammad
Department of Microbiology, Glasgow Caledonian University, Glasgow, Scotland, United Kingdom
Publications
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Research Article
Phenotypic and Genotypic Differences in Invasive and Non-Invasive Strains of Streptococcus pneumoniae
Author(s): Fariha Altaaf* and Abbas Muhammad
Streptococcus pneumoniae (S. pneumoniae) is a human pathogen and a major cause of mortality and morbidity throughout the world. Streptococcus pneumoniae is the causative agent of otitis media, pneumonia, meningitis and bacteremia. Children, elderly and patient with compromised immune system are at a higher risk to attain infection by these bacteria. According to immunochemistry of their capsular polysaccharide, S. pneumoniae has divided into more than 90 serotypes. Many surface proteins are present on S. pneumoniae e.g. surface protein A, pneumolycin, hyaluronate lyase etc. The capsule is a major virulent factor for pneumococci and it prevents the bacteria from phagocytosis by host’s immune system. Some antigenic determinants have also studied for their potential to prompt a protective immune response in different.. View more»