Journal of Carcinogenesis & Mutagenesis

Journal of Carcinogenesis & Mutagenesis
Open Access

ISSN: 2157-2518

Wolfgang Kopp

Wolfgang Kopp
Mariatroster Str. 41, 8043 Graz,

  • Review Article
    Significant Dietary Changes during Human Evolution and the Development of Cancer: From Cells in Trouble to Cells Causing Trouble
    Author(s): Wolfgang KoppWolfgang Kopp

    In all western societies, mortality rates from cancer are high and even increasing. In striking contrast, cancer rates are very rare and even non-existent in primitive cultures, like hunter-gatherer (HG) populations. HGs are free of disease as long as they adhere to their traditional low-insulinemic “Paleolithic” nutrition. With acculturation and transition to current high-carbohydrate/high-insulinemic “Western” diets (HCHIDs), cancer develops in high rates. This paper follows the question of how significant nutritional changes, brought about by the Agricultural revolution, may cause development of cancer. The evidence presented shows that the switch from a Paleolithic to a Western nutrition has brought about significant metabolic perturbations, like an abnormally increased activation of the insulin-like growth factor system, the sympathetic nervous system and .. Read More»
    DOI: 10.4172/2157-2518.1000303

    Abstract PDF

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