Journal of Data Mining in Genomics & Proteomics

Vipan Kumar Sohpal

Publications

• Research Article
  Computational Analysis of Distance and Character based Phylogenetic Tree for Capsid Proteins of Human Herpes Virus
  Author(s): Vipan Kumar Sohpal, Apurba Dey and Amarpal SinghVipan Kumar Sohpal, Apurba Dey and Amarpal Singh
  
  Molecular phylogenetic is a fundamental aspect of evolutionary analysis and depends on distance & character based methods. In this paper, we compare the viral capsid proteins of HHV to analyze the relationship among proteins using substitution models, phylogenetic model with exhaustive search and ME techniques. The effect of Poisson correction with shape parameter on NJ and UPGMA trees also analyze. We show by extensive computer simulation that phylogenetic tree is the reflection of substitution distance. The effect of max-mini branch & bound method and minimini heuristic model and log likelihood associated with character based tree also discussed. We applied ML and MP for perfectly analysis of proteins relationship. We conclude that substitution models, shape parameter, search level and SBL have a critical role to reconstruct phylogenetic tree. Molecular clock study shows tha.. View More»
  DOI: 10.4172/2153-0602.1000128

  Abstract PDF