Indexed In
- Open J Gate
- Academic Keys
- ResearchBible
- China National Knowledge Infrastructure (CNKI)
- Centre for Agriculture and Biosciences International (CABI)
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- CABI full text
- Publons
- Geneva Foundation for Medical Education and Research
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Upma Bagai
Upma Bagai
Chandigarh-160014
India
Publications
-
Research Article
Antimalarial Efficacy of Thalictrum foliolosum (Meadow rue) Against Chloroquine-Resistant P. falciparum
Author(s): Neha Sylvia Walter and Upma BagaiNeha Sylvia Walter and Upma Bagai
Background: Investigation of traditionally used medicinal plants can provide safe and cost effective good antimalarials. The present study explores the in vitro antimalarial potential of Thalictrum foliolosum (meadow rue) leaf extract against Plasmodium falciparum. Methods: Phytochemical screening of the extract was carried out following standardized methods. WHO method based on schizont maturation inhibition was employed to assess the in vitro antiplasmodial activity of plant extract. Colorimetric MTT assay was used to evaluate the in vitro cytotoxicity of Thalictrum foliolosum. Selectivity Index was also calculated. Results: Phytochemical screening of the extract revealed presence of alkaloids, phenols, triterpenes, saponins and phytosterols. Ethanolic leaf extract of Thalictrum foliolosum (ELETF) exhibited IC50<5 μg/ml against chloroquine (CQ) resistant (RKL-9) strains of P.. View More»
DOI: 10.4172/2329-891X.1000163