Journal of Neonatal Biology

Ritu Mehta

Publications

• Case Report
  Congenital Acute Leukemia: A Rare Hematological Malignancy
  Author(s): Vishal Vishnu Tewari, Ritu Mehta and Kunal TewariVishal Vishnu Tewari, Ritu Mehta and Kunal Tewari
  
  Background: Acute leukemia presenting in the neonate and the young infant is a rare hematological malignancy. It may present at birth or within few days (congenital) or it may be diagnosed in first 4-6 weeks of life (neonatal) and may be myeloid or lymphoid in origin. High index of suspicion along with  bone marrow studies, cytochemistry and flow cytometry is the mainstay of diagnosis. Case presentation: We report two cases of congenital acute leukemia presenting in second month of life. The first infant presented with fever, inconsolable crying, loose stools and vomiting of two weeks duration with pallor and hepatosplenomegaly. Lab investigations revealed anemia, leucocytosis and thrombocytopenia with 80% Blasts seen on peripheral blood smear. The bone marrow aspirate was hypercellular with greater than 3% of the blasts positive for my.. View More»
  

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