Raymond W Nims
RMC Pharmaceutical Solutions, Inc., 1851 Lefthand Circle, Suite A, Longmont, CO 80501,
Tanzania
Review Article
Intra-Family and Inter-Family Comparisons for Viral Susceptibility to Heat
Inactivation
Author(s): Raymond W Nims and Mark PlavsicRaymond W Nims and Mark Plavsic
A systematic review of the viral heat inactivation literature for data compatible with modeling using the decimal reduction value/z value approach as well as a new approach based on the power function relationship between decimal reduction value and inactivation temperature is presented. The review has enabled us to conduct quantitative intra-family and inter-family comparisons for various heat inactivation characteristics for viruses, including z value, temperature in°C for 1 log10 and for 4 log10 inactivation in 30 seconds. The parvoviridae family is confirmed to be the most heat resistant of the various virus families for which data were analyzed. .. View More»
DOI:
10.4172/1948-5948.1000112