Journal of Liver

Randa

Publications

• Research Article
  Patho-physiological studies on the Reverse Effect of Curcumin (Curcuma longa, Zingiberaceae) and Ursofalk (Ursodeoxycholic acid) against the Toxicity of Carbon Tetrachloride on Albino Rats
  Author(s): Muhammad MA Salman, Randa and Abdel-RahmanMuhammad MA Salman, Randa and Abdel-Rahman
  
  This study, was established five groups of albino rats to determine the therapeutic effect of Curcuma longa and ursofalk against the toxicity of CC14 in liver and kidney. Group (1) was received orally NaCl 0.9% and used as a normal group. Group (2) was injected intraperitoneal (i.p.) with CCl4 (1 ml/kg), 3 times weekly, for 2 weeks. Group (3) was given orally Ursofalk (100 mg/kg per body weight), group (4) was given orally Curcuma longa (100 mg/kg body weight) and group (5) was given the same doses of Ursofalk plus Curcuma longa for 30 days respectively, post-injected intraperitoneal (i.p.) with CCl4 (1 ml/kg) 3 times weekly, for 2 weeks. Two blood samples were collected, for hematological and biochemical parameters. Specimens from liver and kidney were collected for histopathological examination. Group (2) revealed a highly significant decrease in total RBCs, platelets, Hb and PCV, s.. View More»
  DOI: 10.4172/2167-0889.1000200

  Abstract PDF