Gerontology & Geriatric Research

Pamela Taxel

Publications

• Review Article
  Metabolic Complications of Androgen Deprivation Therapy for the Treatment of Prostate Cancer
  Author(s): Helen Anaedo and Pamela TaxelHelen Anaedo and Pamela Taxel
  
  Aim: Prostate cancer is the most commonly diagnosed cancer and second leading cause of cancer death in U.S. men. The b median age at diagnosis is 67 years, with black men having a 50% higher risk of developing prostate cancer and two-fold mortality rate compared with Caucasians. The use of androgen deprivation therapy (ADT) is associated with symptom control in patients with metastatic prostate cancer but no known survival advantage. This therapy has significant impact on skeletal health, but more recently, the metabolic complications of ADT have been recognized. These include obesity, insulin resistance, diabetes, lipid alterations and cardiovascular health, which will be the focus of this review. Method: We performed a PubMed search (1950-2014) of articles written in English using search terms including prostate cancer, androgen deprivation therapy, gonadotropin-releasing hormone ag.. View More»
  DOI: 10.4172/2167-7182.1000205

  Abstract PDF