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Maricar W. Ching
Maricar W. Ching
Department of Biological Sciences, College of Science and Technology Centro Escolar University, 1005, Manila,
Philippines
Publications
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Research Article
Multiple House Dust Mite Allergen- Sensitization Profiles in Children with Allergic Asthma
Author(s): Jennifer Maries G. Yap, Maricar W. Ching, Cristan Q. Cabanilla and John Donnie A. RamosJennifer Maries G. Yap, Maricar W. Ching, Cristan Q. Cabanilla and John Donnie A. Ramos
Background: Allergic asthma is a common chronic inflammatory disorder which affects populations, with increasing prevalence among children. The risk of developing asthma is uncertain but depends on the interaction of environmental and genetic factors. The role of house dust mite (HDM) allergen exposure in the development of sensitization and asthma remains unclear. Objective: This study determined the sensitization profiles of common HDM species in a population of asthmatic children, which is essential in the development of highly specific and accurate diagnostic and therapeutic strategies for asthma in children. Methods: The immunoglobulin E-binding activity of allergens from the HDM species Blomia tropicalis (Bt), Dermatophagoides farina (Df), and Dermatopahagoides pteronyssinus (Dp) were determined in 250 age- and sexmatched paediatric allergic asthma and non-at.. View More»
DOI: 10.4172/2155-6121.1000179