Manandhar Upasana
China
Case Report
Failure of Remission of Granulocyte-Colony Stimulating Factor G-Csf Induced Drug Eruption Suggestive of Early Psoriasis-A Case Report and Literature Review
Author(s): Manandhar Upasana, Wang Yue Yin, Wu Jian Bo and Song Ji QuanManandhar Upasana, Wang Yue Yin, Wu Jian Bo and Song Ji Quan
Human Recombinant Granulocyte colony-stimulating factor is a hematopoietic growth factor; most commonly known to be used for chemotherapy-induced neutropenia for the mobilization of peripheral blood stem cells. A case of 43 years old lady, post radical mastectomy for breast cancer and one cycle of chemotherapy was encountered with the development of massive psoriasis-like eruptions all over the body including the scalp with adherent silvery scales after 10 days of administration of granulocyte colony-stimulating factor with the failure of remission even after months of treatment. Specific psoriasis signs were seen positive but the Biopsy and Reflectance Confocal Microscopy was inconclusive for the diagnosis of Psoriasis, therefore managed as an allergic drug eruption with immediate cessation of G-CSF administration. The rash improved significantly with no new appearances. However duri.. View More»
