Jorge Olmos
Department of Marine Biotechnology, Centro de Investigacion Cientifica y de Educacion Superior de Ensenada (CICESE), Ensenada, B.C.,
Mexico
Research Article
Apoptosis Comparison Effects Between Synthetic and Natural B-Carotene from Dunaliella salina on MDA-MB-231Brest Cancer Cells
Author(s): Jorge Olmos, Rocío Gómez and Viviana P. RubioJorge Olmos, Rocío Gómez and Viviana P. Rubio
Dunaliella salina is genus most important species for β-carotene production. Several investigations have demonstrated that D. salina produces more than 10% of its dry mass. β-carotene is an important pro-vitamin A source and can also act as a lipid radical scavenger and as a singlet oxygen quencher. Vitamin A Deficiency (VAD) has been related with cancer, for this reason synthetic and natural β-carotene has been used for prevention and treatment of the disease. Synthetic β-carotene is cheaper than natural molecule but only contains all-trans-β-carotene (ATβC), while 9-cis-β-carotene (9CβC) and ATβC are both produce by D. salina. Meta-analysis of controlled trials using high levels of synthetic β-carotene supplementation in smoker’s individuals, mention that instead to prevent and control lung cancer, .. View More»
DOI:
10.4172/1948-5948.1000181