James M Greenberg
Tanzania
Research Article
Cincinnati Regional Incidence, Morbidity, and Mortality of Neonatal Foregut Defects and High Coincidence with Cardiovascular Malformations
Author(s): Alan P Kenny, Meredith Tabangin, Eric Hall, Koryse Woodrooffe, Wendy Lai, Jareen Meinzen-Derr, Robert J Hopkin and James M GreenbergAlan P Kenny, Meredith Tabangin, Eric Hall, Koryse Woodrooffe, Wendy Lai, Jareen Meinzen-Derr, Robert J Hopkin and James M Greenberg
The first trimester fetal foregut generates organs from larynx to ligament of Treitz. The incidence and clinical impact of many of the 29 congenital malformations arising from the foregut organs remain under characterized. We performed a retrospective chart review on patients from a geographically defined area born between 2006 and 2008 admitted to Cincinnati Children’s Hospital Neonatal Intensive Care Unit with diagnoses consistent with one or more congenital foregut malformations.
We found foregut malformations occurred in 1 in 801 births and determined the incidence for each individual foregut malformation, including some that have not previously been reported. We report a high rate of multiple congenital foregut malformations within an individual with coincidence of foregut malformations of 51.5%, and a high association with cardiovascular malformations (40%).. View More»
DOI:
10.4172/2167-0897.1000115