Cardiovascular Pharmacology: Open Access

Hongwei Fu

Publications

• Review Article
  Early Subclinical Biomarkers in Onco-Cardiology to Prevent Cardiac Death
  Author(s): Yajun Gu, Bumei Zhang, Hongwei Fu, Yichao Wang and Yunde LiuYajun Gu, Bumei Zhang, Hongwei Fu, Yichao Wang and Yunde Liu
  
  Recent oncologic treatment has been associated with cardiovascular complications, such as hypertension, metabolic derangements, thrombosis, arrhythmia, and even cardiac death. Careful attention to detailed cardiac evaluation is required to optimize the anticancer treatment and prevent heart failure of patients undergoing chemoradiotherapy. Classical cardiovascular biomarkers like ANP, BNP, ProANP, NT-ProBNP, hsTnI, hsTnT, adropin, copeptin, and ET-1 are indicative of toxic effects in cancer patients with radiation, chemotherapy, and neoadjuvant treatment. Recently, miRNAs (i.e., miR-29, miR-146, miR-208, and miR-216) in the peripheral blood or exosome-derived miRNAs are attractive as novel biomarkers for drug-induced cardiotoxicity due to their highly conserved sequence and stability in body fluids. The anticancer treatment could lead to detectable increases of miRNAs.. View More»
  DOI: 10.4172/2329-6607.1000183

  Abstract PDF