Journal of Clinical & Experimental Pharmacology

Gani Dragusha

Publications

• Research Article
  Constrictor Action of Substances in the Pulmonary Artery in Newborn with the Amnional Fluid Aspiration Syndrome (MAS)
  Author(s): Hilmi Islami, Ragip Shabani, Naim Haliti, Gani Dragusha, Bajram Nuraj and Salih AhmetiHilmi Islami, Ragip Shabani, Naim Haliti, Gani Dragusha, Bajram Nuraj and Salih Ahmeti
  
  In this in vitro work, action of acetylcholine and histamine on pulmonary artery in live and dead newborn (250 up to 3000g of body weight) which have died due to aspiration of amnional fluid was studied. Response of tracheal rings and pulmonary artery preparations on acetylcholine 10-4, 10-3, 10-2, 10-1 mol/dm3; and histamine: 10-4, 10-3, 10-2, 10-1 mol/dm3 followed up. Response of tracheal smooth musculature was registered in a multi-channel registration (Watanabe HSE 6600) Statcham. The action of acetylcholine in the pulmonary artery, in cases which has died due to aspiration of amnional fluid, has not experienced any significant change (p > 0.1), whilst histamine has caused constriction of the pulmonary artery in a significant manner (p < 0.01). Despite this, examination of tracheal rings in the controlling group with the meconial aspiration syndrome (MAS) and the group with lung atel.. View More»
  DOI: 10.4172/2161-1459.1000104

  Abstract PDF