Arun Chudhury
India
Research Article
Determination of Source of Hyperandrogenism and Comparisons of Hormonal and Metabolic Profile in Different Phenotype of PCOS: A Hospital Based Study
Author(s): Ritesh Agrawala, Arun Chudhury, Binoy Mohanty, Anoj Baliarsinha and Suchita AgarwalRitesh Agrawala, Arun Chudhury, Binoy Mohanty, Anoj Baliarsinha and Suchita Agarwal
Objective: Metabolic parameters in polycystic ovary syndrome (PCOS) correlate to their phenotypic presentations and sources of hyperandrogenism. Till date no studies have evaluated the source of hyperandrogenism among phenotypic variants of PCOS. Therefore we determined the sources of hyperandrogenism and compared the metabolic parameters in different phenotypes of PCOS.
Material method: Study included 120 PCOS patients and 15 age matched controls. PCOS were diagnosed by revised Rotterdam criteria (2003). Different phenotypic presentations like polycystic ovary (P), ovulatory dysfunction (O) and hyperandrogenism (H) were evaluated and compared for anthropometrical, hormonal and metabolic parameters. They were correlated with the source of androgen excess following post Leuprolide acetate (20 μg/kg) 17-OHP and post synacthen (250 μg) DH.. View More»
