Dermatology Case Reports

ISSN - 2684-124X

Alan D Widgerow

Alan D Widgerow

Irvine and Chief Medical Officer Alastin Skin Care, 3129 Tiger Run Court #109, Carlsbad, CA 92010
Tanzania

Publications
  • Case Report
    Histological Changes Associated with Extracellular Matrix-Remodeling Topical Therapy
    Author(s): Antoanella Calame and Alan D WidgerowAntoanella Calame and Alan D Widgerow

    Introduction: An innovative skincare product line incorporating a proprietary blend of selected peptides and botanicals formulation has been developed with the aim of preparing skin surfaces for rejuvenating procedures and for their long-term maintenance. The premise is to clear the extracellular matrix (ECM) of accumulated waste products improving cellular ECM cross talk enabling efficient collagenesis and elastogenesis to follow. Methods: To validate this scientific narrative and examine efficacy without the use of rejuvenating devices, we have undertaken a series of histological examinations in 5 subjects in their 60s assessing changes following isolated topical application of product to the skin. Results: From a histological perspective, our findings showed significant changes within the ECM, with new collagen format.. View More»

    DOI: 10.35248/2684-124X.17.2.126

    Abstract PDF

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