Ahmed Esmael
Department of Microbiology, Immunology and Parasitology, Debre Markos University,
Ethiopia
Research Article
Drug Resistance Pattern of Mycobacterium tuberculosis in Eastern
Amhara Regional State, Ethiopia
Author(s): Ahmed Esmael, Ibrahim Ali, Mulualem Agonafir, Mengistu Endris, Muluworke Getahun, Zelalem Yaregal and Kassu DestaAhmed Esmael, Ibrahim Ali, Mulualem Agonafir, Mengistu Endris, Muluworke Getahun, Zelalem Yaregal and Kassu Desta
Background: Tuberculosis (TB) is a major public health problem in Amhara region, Ethiopia where the TB case detection rate is low (22%). This situation has been worsened by the emergence and spread of drug resistance strains which have been threatening efforts of TB control. Objectives: The aim of this study was to assess the magnitude of drug resistance patterns of M. tuberculosis in Eastern Amhara region, Ethiopia. Methods: A facility based cross sectional study was conducted among 230 (165 new and 65 retreated) smear positive TB patients (age ≥18 years old) from September 2010 to June 2011. Socio-demographic data of the study participants and possible factors for development of drug resistance were collected using pre-tested structured questionnaire. Smear positive sputum samples were processed and decontaminated by the modified Petrof method. Primary isolation and drug suscepti.. View More»
DOI:
10.4172/1948-5948.1000125