Journal of Thyroid Disorders & Therapy
Open Access

Abstract

Value of SPECT/CT in Cervical Vertebra Metastasis Mimicking Residual Thyroid Tissue on Planar I-131 Scan

Aylin Oral, Ozgur Omur, Bulent Yazici and Aysegul Akgun

A total thyroidectomy was performed on a 62 year-old male patient with 3.5 cm cold nodule and diagnosis of
differentiated thyroid carcinoma was made. He received 200 mCi of I-131 because pulmonary metastases were founded on computed tomography and his serum thyroglobulin level was high (>300 ng/ml). Post-therapy planar whole body scan showed diffuse pulmonary tracer accumulation consistent with pulmonary metastases, 3 foci of activities in the thyroid region of neck and physiological tracer uptake in the liver. Initially, it was considered that high serum thyroglobulin level was caused by pulmonary metastases and activities in the neck were due to residual thyroid tissue. But, single photon emission computed tomography/computed tomography (SPECT/CT) images demonstrated that the activity in the midline of the neck was originated in the cervical (C5-6) vertebra due to bone metastasis. Cervical vertebra metastasis in the same level with probable residual thyroid tissue in planar I-131 whole body scan can be easily overlooked. We considered that the complementary SPECT/CT for head and neck region should be used not only in the selected differentiated thyroid patients with unexpected abnormal activity
but also in patients with expected residual thyroid tissue, salivary gland or mouth activity in planar I-131 whole body scan.