Background: Radiofrequency ablation has been reported to be effective and safe in reducing benign thyroid volume nodules. Most studies carried out so far were performed on a limited number of large nodules and often a subset of them required more than one single treatment.
Case report: We describe the case of 82-year-old woman with a very large volume thyroid nodule treated with a single session of thyroid radiofrequency ablation. After six months, the patient showed significant improvement of compression symptoms and significant volume reduction of 68% (from 152 mL to 48 mL).
Methods: To our knowledge, this is the first case report so far that proves the effectiveness and safety of radiofrequency ablation in such a large thyroid nodule.
Conclusions: Radiofrequency ablation is very effective technique for the percutaneous treatment of thyroid nodules. Further data are needed to define the effectiveness and the feasibility in treating large thyroid nodules.