Anatomy & Physiology: Current Research
Open Access

Abstract

The Role of Connective Tissue Anatomy in Musculoskeletal Disorders

Mei Ling Chou

Connective tissues form the structural framework of the musculoskeletal system by linking muscles, bones, joints, nerves and blood vessels into an integrated functional network. Traditionally regarded as passive supporting structures, connective tissues are now recognized as dynamic biological systems that continuously adapt to mechanical loading, biochemical signaling, and physiological stress [1]. Their ability to remodel throughout life is essential for maintaining tissue integrity and supporting efficient movement. The extracellular Matrix (ECM) is the principal structural component of connective tissues. Composed primarily of collagen, elastin, proteoglycans, glycosaminoglycans and adhesive glycoproteins, the ECM provides both mechanical strength and biological signaling functions [2]. Disturbances in these regulatory mechanisms contribute to tissue degeneration, fibrosis and impaired healing [3]. Recent anatomical studies have substantially expanded knowledge of fascial tissues. Rather than functioning solely as connective coverings, fasciae

Published Date: 2025-04-02; Received Date: 2025-03-03