Biochemistry & Pharmacology: Open Access
Open Access

Abstract

Structural and Functional Insights into Receptor-Ligand Interactions in Drug Design and Pharmacodynamics

Harriet Langford*

The understanding of receptor-ligand interactions has become a foundational pillar in modern drug design and pharmacodynamics. These interactions are central to the biological activity of drugs, governing both the specificity and efficacy of therapeutic agents. Receptors, often proteins situated on the surface or within cells, are targets to which ligands either endogenous molecules like hormones or exogenous compounds such as drugs bind to initiate a biological response. The precise interaction between these molecules dictates the pharmacological outcome, making it a critical focal point for pharmaceutical research. The structural and functional characterization of these interactions enables rational drug design, where molecules can be engineered to fit the target receptor with high specificity and desired activity.

Published Date: 2025-03-04; Received Date: 2025-02-03