Contemporary organisations have to search for new strategic ways in order to improve economic effectiveness and work productivity, as well as to maintain human resources in long term. Managers should ensure open management of changes in order to motivate employees to participate in it delegating more responsibility to employees. This can promote trust, support employees’ initiatives in operations improvement thus changing traditional organizational structure to flexible operations management. Therefore combined approach of macro- and micro-ergonomics in strategic operations management can result in effective improvement of labour productivity, management of technologies and healthy work environment. The developed model “Ergonomics implementation in operations management”, based on the overview of the recent prominent literature, shows that changes in operations management due to ergonomics implementation stimulate satisfaction of employees, increase productivity, and decrease costs resulting in an improvement of the process and product quality.