Journal of Nanomedicine & Biotherapeutic Discovery
Open Access

Abstract

Silver Nanoparticles Biosynthesis by Fusarium oxysporum and Determination of its Antimicrobial Potency

Nida Tabassum Khan, Mahum Jameel and Jibran Jameel

Nanotechnology encompasses the engineering of nanoparticles with enhanced functionality and improved stability which is quite different from the bulk form of the same material. Fungi as bionanofactories for the production of diverse metallic nanocrystals is the right choice because it not only offers an ecofriendly and cost effective procedure but also provide easy and simple down streaming for product recovery. Fungal filtrate of Fusarium oxysporum isolated from banana fruit was used for the amalgamation of silver nanoparticles. Appearance of light brown colour of fungal filtrate upon incubation with AgNO3 indicates silver nanoparticle formation with strong absorption in the visible region at 440 nm as determined by ultra violet visible spectroscopy. Disc diffusion assay showed enhanced antibacterial and antifungal activity of silver nanoparticles against pathogens like Candida albicans, Escherichia coli, Candida krusei, Staphylococcus aureus and Aspergillus flavus.