GET THE APP

Acute and Chronic Disease Reports

Acute and Chronic Disease Reports
Open Access

+44 1223 790975

Abstract

Serotonin Level and Nutritional Behavior of Patients with Primary InsulinResistance

Kurnikova Irina, Nikishova TV and Sargar RV

Background: One of the most important tasks at the initial stage of treatment of patients with primary insulin resistance is a decrease in body weight, which means a decrease in the amount of food consumed. Patients rarely manage to cope with this task independently, and drug therapy does not always provide sufficient effect.

Methods: Patients (42 people) aged 38.4 ± 2.0 years, body mass index (BMI) 32.3 ± 4.2 kg/m2. Two groups of observation were formed: group 1 (20 people) received reflexotherapy using special corporal and auricular points and a hypocaloric diet. Patients of the 2nd group (22 people) were given only a diet was studied: BMI, the ratio of WC/HC, HOMA-IR index, insulin and C-peptide. ELISA (Labor Diagnostica NORT Serotonin RESEARCH ELISA, Germany) determined serotonin in serum. The reflexotherapy procedures included daily corporal and auricular acupuncture.

Results: Based on the results of their own research, it has been shown that the use of reflex therapy using special corporal and auricular points with obese patients contributes to serotonin in the blood serum and leads to rapid satiety during eating. This allows patients to observe a low caloric diet at the initial stage of treatment. It is also shown that the increase in serotonin in the serum is statistically significant only when the combination of the therapeutic diet with reflex therapy, but not in the case of exclusively dietary correction.

Conclusion: The use of reflexotherapy with the use of special corporal and auricular points promoted the increase of serotonin in the blood serum and led to rapid satiety during eating. This allowed patients to observe a hypocaloric diet at the initial stage of treatment.

Top