Thromboembolic disorders are very common across world, frequently a leading cause of death. Appropriate use of Anticoagulant plays an important role in management of prevention and treatment thromboembolic disorders like Deep vein thrombosis, Pulmonary embolism, Stroke prevention in atrial fibrillation, prosthetic heart valves etc. Vitamin K antagonists, e.g., acenocoumerol or warfarin are frequently used as oral anticoagulants worldwide over 50 years in clinical practice. Anticoagulation management never complete with Five Cs i.e. complications, compliance, confidence, convenience and cost and success of anticoagulation management totally depends upon five Cs of anticoagulation. The association between patient knowledge and enhanced anticoagulation control is well documented. Patient education in anticoagulation management as well as well-defined regular patient education programs leads to increase adherence to the therapy and definitely good compliance. Good compliance also develops confidence and reduces the complications because of anticoagulation therapy. Anticoagulation clinics will definitely have a role in anticoagulation management but in country like India they are very few. Self-monitoring device are available in India but because of coast factor and lack of awareness not getting utilised at patient level.