Background: Psoriasis is a very common, chronic inflammatory and proliferative skin disease with different clinical forms that can affect males and females.In recent years psoriasis has been linked lately to different systemic disease associated with numerous multi-organ abnormalities and complications. Psoriasis is related to elevated cholesterol levels and triglycerides levels and this will be important in the management of it.So their is a great need to study lipid abnormalities in psoriatic patients, which will help us to evaluate the level of risk individuals for developing atherosclerosis and vascular obstructive disorders, as well as associated morbidity and mortality.
Methods: Fifty Patients (27 male and 23 female) with different types and severity of psoriasis, 50 persons (28 male and 22 female) as controls. Serum total cholesterol (TC) High density lipoprotein, Low density lipoprotein (LDL), Triglycerides (TG). Serum total cholesterol, triglyceride and HDL-C were measured by using Spin react kit.
Results: Serum lipid profile levels in the psoriasis group shows that the range of serum cholesterol level was 132 to 307 with a mean of (201 ± 33, 4) mg%. The range of serum low density lipoprotein cholesterol (LDL-C) was 87 to 254 with a mean of (138 ± 33.4) mg%. The range of triglyceride was 60 to 236 with a mean of (149.7 ± 36) mg%. The range of serum high density lipoprotein cholesterol (HDL-C) was 21 to 44 with a mean of (31.5 ± 5) mg%.
Conclusion: The results of this study conclude that cholesterol, LDL and triglyceride levels were previously reported to be higher in psoriasis patients while HDL levels were previously reported to be low which makes a difference in the severity of psoriasis.