Drug Designing: Open Access
Open Access
ISSN: 2169-0138
ISSN: 2169-0138
The work that I have chosen is to treat anaemia, a disorder that affects mostly children and women which is prominently because of the iron deficiency in the nutrition. Deficiency of iron at this phase of life affects development of brain and might have uncontrolled results on cognitive development. Iron deficiency anemia was evaluated to predict that 40%-60% of brain impairment, predominantly 6-24 months from under developed countries. Drosophila melanogaster also called common fruit fly is a well-studied, considered and highly monitored model organism for genetics for comprehending molecular mechanisms of human illness. Many fundamental physiological, biological and neurological characteristics are preserved between mammals and fruit fly and about 75% of human pathogenic genes are predicted to contain functioning homologin the fly. Moringa oleifera’s methanolic extraction of leaf has high value of free radical scavenging property. M. oleifera leaf supplementation enhances mortality, locomotion and capacity of reproduction in fruit fly. Hence Moringa oleifera leaf is considered to be safe and may be considered in the management of impact that predisposes to free radical insults. Our main goal is to develop a drug to find a remedy for this disease using polyphenols which are found abundantly in Moringa oleifera. Polyphenols prevent anaemic disorder that cause iron deficiency and also provides other nutritional benefits.
Published Date: 2025-04-18; Received Date: 2024-11-15