Cell & Developmental Biology
Open Access

Abstract

Hypertensive female patient with sever muscle wekaness , can we cure some or all her problems ?

Mr. R Albitar graduated from faculty of medicine 2008 , Cairo University

A 44 years old , female patient mother of 2 children, with no special habits of medical importance , hypertensive in the last 14 years on 4 antihypertensive drugs (thiazides , ACE I , CCB and BB ) with poorly controlled hypertension , She presented by Generalized weakness for 2 years which started in gradual onset , progressive coarse in the last 2 years as bilateral and symmetrical proximal muscle weakness in both upper and lower limbs that render the patient unable to go upstairs or comb herself . the Weakness extended to became generalized in the few months , The patient sought medical advice repeatedly at neurology clinics where she was asked for MRI L/S that revealed multiple minor disc lesion for which she was prescribed steroids , muscle relaxant and vitamin B12 with no improvement. 3 months ago the weakness worsen more and more up to head drop for which she presented to ER where investigations revealed severe hypokalemia K ( 1.3 mmol/L) ,with the proper I.V potassium replacement the patient weakness improved dramatically , with regaining of the full muscle power in 2 days , serum Aldosteron Renine Ratio ( ARR) 271 –normal up to 20 - that confirmed primary aldosteronism , CT abdomen revealed lt adrenal mass 8 mm , The patient underwent laparoscopic supra renal adrenalectomy , with smooth post operative care , now she cured HTN with normal muscle power.

Published Date: 2020-08-31;