Introduction: Severity of injury and serum amylase and lipase concentrations are parameters used to assess the grade of pancreatic injury. It is still unclear in what way amylase and lipase are related to the grade of injury or the injury outcome. We thus hypothesize that the serum amylase and lipase concentrations as well the urine amylase one maybe prediction biomarkers in blunt pancreatic trauma cases.
Methods: The study took place in a Tertiary Pediatric Hospital of Athens-Greece. The initial elevation of the serum amylase and lipase concentrations as well as the urine amylase ones were analyzed and related to age, ISS score and outcomes.
Results: Fifteen patients were included (eight males and seven females). The mean age was nine years old (3– 15 years old) and the mean ISS score was 5 (2–9). Four patients developed post-traumatic pancreatic pseudocyst (P.P.C). Patients with increased serum amylase, lipase and urine amylase concentrations and ISS score more than 8 developed P.P.C.
Conclusion: The increased serum amylase and lipase values as well as the urine amylase ones, combined with a high ISS score grade may have prediction value in blunt pancreatic trauma cases