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Y.J. Oyeniyi1*, F.B.O. Mojiminiyi2
Background: Hibiscus sabdariffa L. family Malvaceae is a perennial herbaceous medicinal shrub widely cultivated for its proven anti-hypertensive property Objectives: The focus of this investigation is to formulate the aqueous extract of HS as oral tablets for accurate dosing and to ease the administration of the aqueous extract. Method: Five formulations of HS granules were prepared by wet granulation technique and thereafter the flow characteristics of the granules were assessed through, angle of repose, Hausner’s ratio, density measurements, moisture content and compressibility index determinations. Heckel and Kawakita analyses were however employed to study HS granules compactability, while the United State Pharmacopeia 2012 (USP) quality control tests were used to investigate the tabletting properties.
Published Date: 2021-11-18;