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Pharmaceutical drug has been widely prescribed by physicians in providing appropriate chemical composition to the patients for remedial action. Every drug name is being referenced by multiple brand names in the pharmaceutical industry for marketing the same drug with different brand names to elevate a product. This overwhelming competition across the globe for each brand name provoke the doctors, pharmacist, vendors and medical representatives to be familiar with brand names of the same drug as a ready reckoned. In this paper, drug alias retrieval using regular expression has shown significant improvement in Precision and a fair result for Recall, and F-Score.