Drug Designing: Open Access
Open Access

Abstract

Design and Synthesis of Novel Antiviral Agents Against Emerging RNA Viruses

Mikkel Rasmussen*

Emerging RNA viruses represent a persistent and evolving threat to global public health, as evidenced by outbreaks of Ebola, Zika, Chikungunya, and most notably, SARS-CoV-2. The rapid mutation rates, zoonotic potential, and capacity to spread across populations make RNA viruses particularly difficult to control using traditional therapeutic strategies. In response, the design and synthesis of novel antiviral agents targeting conserved viral mechanisms has become a critical area of medicinal chemistry. The development of such agents requires a multidisciplinary approach that incorporates virology, molecular modeling, organic synthesis, and pharmacology. By understanding viral replication mechanisms at the molecular level, researchers can identify vulnerable targets and design molecules capable of interrupting the viral life cycle effectively.

Published Date: 2025-03-04; Received Date: 2025-02-03