Chemotherapy: Open Access

Chemotherapy: Open Access
Open Access

ISSN: 2167-7700



Biphasic Effect of Arsenic on Cell Growth and Its Clinical Significance

Dianjun Sun and Kewei Wang

Arsenic stimulates proliferation at low levels and inhibits cell growth at high concentrations, showing a biphasic effect on biological process. The biphasic effect requires that arsenic concentration has to be maintained at an appropriate threshold during chemotherapy. The apoptosis may be a primary mechanism related to dual properties of the arsenic.

Published Date: 2019-06-03; Received Date: 2019-05-20