Biochemistry & Pharmacology: Open Access
Open Access

Abstract

Biological and Solid-State Nanopores for DNA Sequencing

Chi Lu and Ping Yu

History and current developments of nanopores for DNA sequencing are reviewed. Discussions are primarily carried out on the two major categories of the devices, biological and solid-state nanopores. Hybrid nanopores are also mentioned. Difficulties defying practical applications are demonstrated as well as some possible improvements. A brief prospect is given in addition.