Premature Ovarian Failure (POF) that leads to secondary amenorrhea is caused by early depletion of ovarian follicles. Therapeutic methods have been described for treating infertility in POF but even with these therapies the probability of pregnancy remains so low. However, some spontaneous gestations are reported in these patients.
In this report, we describe a young woman with diagnosed POF from two years earlier who referred to our emergency department with the possibility of acute appendicitis. Her chief complaint was periodic abdominal pain that had been started 4 hours before presenting to emergency room. During her staying in the emergency room for further investigations, the patient delivered a normal baby without even being aware of pregnancy throughout this period. The neonate was term and male. The Apgar score was 7 in the first minute after birth which rapidly improve to 10 in tenth minute after providing immediate suction, repositioning and stimulation the neonate. More evaluations of child didn’t show any abnormality in child or a significant morbidity in both mother and child.
POF is a condition that leads to secondary amenorrhea in women younger than 40 years. In this case, the patient didn’t use any contraception due to POF diagnosis. It is important to consider the low possibility of getting pregnant, especially in patients who don’t desire pregnancy. The mechanisms of spontaneous pregnancy in POF and attributing factors in these mechanisms are issues that need further investigations.