Biochemistry & Pharmacology: Open Access
Open Access

Abstract

Advanced Nanocarrier-Based Drug Delivery Systems: Biochemical Principles and Pharmacological Applications

Catarina Moura*

Nanocarrier-based drug delivery systems have emerged as one of the most promising technologies in modern pharmaceutical science. Their ability to improve the bioavailability, targeted delivery, and controlled release of therapeutics offers substantial benefits over conventional drug delivery approaches. These nanocarriers ranging from liposomes, dendrimers, polymeric nanoparticles, micelles, to solid lipid nanoparticles are engineered to encapsulate drugs, protect them from degradation, and transport them across biological barriers to specific target sites. The fundamental biochemical principles behind their operation involve the exploitation of nanoscale interactions, surface modifications with ligands for active targeting, and responsiveness to internal (pH, redox) or external (temperature, magnetic field) stimuli for controlled drug release.

Received Date: 2025-02-03