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The integration of molecular biology with engineering leads to development of an emerging field in research known as synthetic biology. This work will support the progress in designing and construction of synthetic genetic products. Computational methods would improve the predictability of respective mechanisms and the analysis along with the interpretation of both qualitative and quantitative models will become important. The present review article is a diagrammatic or schematic representation of an overview of synthetic biology, computational methodology, techniques, models and steps involved in designing, components used and tools, softwares and databases used with their applications.