Journal of Pharmacovigilance

Molecular Imaging and Drug Delivery

Drug delivery technology has been recognized as one of the most important commercial projects in the pharmaceutical industry. An ideal drug delivery system can transport active ingredients to an exact location in the body and maintain the desired concentration. Reformulations of approved active substances were pursued enthusiastically for improving drug solubility, biodistribution, and half-lives (e.g. liposomal anthracyclines and nab-paclitaxel). On the other hand, molecular imaging also markedly facilitated the development of new drugs in the era of precision medicine. The introduction of MRI (magnetic resonance imaging), PET (positron emission tomography), SPECT (single photon emission computed tomography) etc. opens new perspectives in drug delivery. Contrast agents with disease biomarkers further help to achieve early detection followed disease treatment. It is worth to note that the combination of targeted therapy, controlled release, and molecular imaging has become a trend. These promising results lead to the growing up applications in the field of real-time monitoring therapy and personalized medicine