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The diseases that infect not only organs as well as body are known as systemic diseases. Usually the general medicine doctors treat these issues by general medication. In these cases some basic analysis techniques are used and biochemical tests to detect infectious agent for disease.
Condition of hands reflects several conditions of human body leading to systemic disease. Hands compose of several tissues, blood vessels, bones etc. and any abnormality leads to affecting whole body and this is systemic diseases. Arthritic Swelling, Dactylitis, Mucous Cyst etc. are most common types of systemic diseases. Fever , Sweating , Weight loss etc. are some of the symptoms of systemic diseases.
Related Journals of Systemic disease
General Medicine: Open Access, Internal Medicine: Open Access, Journal of General Practice, Journal of General Physiology