The Integrated Project Nanobiopharmaceutics aims at the development of innovative multidisciplinary approaches for the design, synthesis and evaluation of functionalised nano-carriers and nano-particle-based micro-carriers for the treatment of various diseases based on targeted, controlled delivery of therapeutic peptides and proteins (biopharmaceutics).
Design, synthesis and functionalization of novel nano-carriers and nano-particle-based micro-carriers for targeted delivery of P/P drugs via oral, pulmonary and Blood Brain Barrier (BBB) crossing administration routes. Toxicological screening of the nano-carriers and investigation of the release profile of P/P drug under various environmental conditions and the assessment of the biocompatibility and biodegradability of the new formulations. Novel pulmonary P/P carriers with improved delivery features to overcome the administration difficulties and increase efficiency of protein delivery to the deep lung. Oral nano-particulate P/P carrier systems capable of adhering to the gastrointestinal mucosa and also displaying protective and permeation enhancing properties. Establishment of an in vitro model for the assessment of nano-carriers permeability through the Blood Brain Barrier (BBB).
Related Journals of Nanobiopharmaceutics
Journal of Nanomedicine & Biotherapeutic Discovery, Journal of Obsessive-Compulsive and Related Disorders, Journal of Homotopy and Related Structures, Journal of Venomous Animals and Toxins including Tropical Diseases