Journal of Pharmacogenomics & Pharmacoproteomics

The finite element analysis of risk of lumbar fatigue for 55-65 years old Chinese female who act as stayhome grandchildren sitter

5^th International Conference on Predictive, Preventive and Personalized Medicine & Molecular Diagnostics

December 01-02, 2016 Valencia, Spain

Na Li, Lu Yang, Haoran Xing, Ping Yan, Xu Wang, Jingjing Chen and Kun Xiong

Xiangya Medical School, Central South University, Changsha, China

Posters & Accepted Abstracts: J Pharmacogenomics Pharmacoproteomics

Abstract:

Up to 22% Chinese adults (50 years and older) have suffered from low back pain caused by chronic lumbar fatigue under the long-term effect of physiological and external loading. The epidemiological data shows that the bone fracture risk of female out of bone fatigue is 1.1-21%, higher than that of male. Up to 66.47% of the 55-65 years old Chinese female stayed home and acted as grandchildren sitter (e.g., holding kid in daily life) because the mothers returned to work in 6 months after giving birth. In consequence of these frequently external loading, the chronic lumbar fatigue probably caused higher risk of lumbar degeneration and fatigue. In this study, the Chinese 55-65 years old female and normal (serve as control) lumbar finite element model (FEM) were developed and validated. The material properties of old female lumbar vertebra was modified according to degenerated bone mineral density and geometry was adjusted based on old female�??s intervertebral disc height. The motion of holding kid was simulated by old female FEM and the stress distribution was calculated. The results indicated that the pressure of posterior lateral edge of lumbar intervertebral disc was significantly higher (20.9%) than that of the normal, the pressure of the L4 bottom vertebra and L5 upper vertebra was also higher (16.68%) than that of normal. These results imply that the holding kid motion could increase the lumbar fatigue risk of old female and the old female should decrease the frequency of the motion of holding kids in the daily life. This study could contribute to give 55-65 years old female suggestion how to avoid lumbar vertebral fatigue by predicting high risk.

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