Journal of Blood Disorders & Transfusion

Phase angle from bioelectric impedance: A new potential tool to assess nutritional status and mortality risk among children and adolescents undergoing hematopoietic stem cell transplantation

International Conference on Hematology & Blood Disorders

September 23-25, 2013 DoubleTree by Hilton Hotel Raleigh-Durham Airport at RTP, NC, USA

Regina MariaVilela

Accepted Abstracts: J Blood Disord Transfus

Abstract:

During the course of hematopoietic stem cell transplantation (HSCT) treatment, the decrease in food intake and increased metabolic rates contribute to malnutrition. Considering that the nutritional status has been used as a prognostic factor for patients undergoing hematopoietic stem cell transplantation (HSCT), the nutritional assessment during the pre-transplant phase becomes important to identify patients at nutritional risk or with malnutrition in order to address nutritional therapy and improve the treatment results. Recently, by using Bioelectrical Impedance Analysis (BIA), malnutrition began to be detected in a variety of clinical conditions by changes in phase angle (PA) that seems to be related to cell death or a change in selective permeability of membranes, compromising cell integrity and fluid balance. These changes can be observed prior to changes in anthropometric and laboratory values. The use of standardized PA as an indicator of survival and nutritional status for patients undergoing HSCT will be presented and discussed.

Biography :

Regina MariaVilela obtained her Masters degree in Biochemistry from Federal University of Paran? (Brazil) and her Ph.D. degree in Human Nutrition from McGill University- School of Dietetic and Human Nutrition (Canada). She received the Honor Award ?Professional of the year? in 2001 from the Paran?/S?o Paulo/Sta. Catarina Dietetic Association and has been honored by the undergraduate students in more than twenty convocations since 1992 when started her carrier as a professor. Currently, her researches are focused on Nutritional Diagnosis and Intervention, especially on the following topics: clinical nutrition in hematopoietic stem cell transplantation; clinical nutrition in immunology and oxidative stress.