Ligand-directed therapy and molecular imaging based on in vivo phage display technology
3rd International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems
April 08-10, 2013 Hilton Chicago/Northbrook, USA

Renata Pasqualini and Wadih Arap

Accepted Abstracts Oral: Pharmaceut Anal Acta

Abstract:

We have developed in vivo phage display, a functional peptide screening established in animal models and later in patients. Isolation of homing peptides enables subsequent identification of tissue-specific receptors. Systematic implementation of this strategy will lead to the construction of a comprehensive map of vascular markers in each organ, tissue, or disease, and may result in a new pharmacology.